| Thomas Middleditch | Richard Hendricks |
| T.J. Miller | Erlich Bachman |
| Josh Brener | Nelson 'Big Head' Bighetti |
| Martin Starr | Bertram Gilfoyle |
| Kumail Nanjiani | Dinesh Chugtai |
| Amanda Crew | Monica Hall |
| Zach Woods | Donald 'Jared' Dunn |
| Matt Ross | Gavin Belson |
| Suzanne Cryer | Laurie Bream
(credit only) |
| Jimmy O. Yang | Jian Yang
(credit only) |
| Ben Feldman | Ron LaFlamme |
| Ian Alda | Marc |
| Chris Diamantopoulos | Russ Hanneman |
| J.J. Nolan | Karen
(as JJ Nolan) |
| Romy Rosemont | Molly Kendall |
| Alice Wetterlund | Carla Walton |
| Joshua Chang | Seth |
| Anna Khaja | Rachel |
| David Lewison | Business Manager |
| Amber Plaster | EndFrame Receptionist |
| Maverick Thompson | Aspen |
| Ping Wu | Henry |
| Alexander Michael Helisek | Claude
(uncredited) |
| Matt Houston | d-keen CEO
(uncredited) |
| Brian A. Pollack | Valet
(uncredited) |
| Annie Sims | Hotel Guest
(uncredited) |
| Napoleon Tavale | Jim
(uncredited) |