| Patrick Stewart | Capt. Jean-Luc Picard |
| Jonathan Frakes | Cmdr. William Riker |
| LeVar Burton | Lt. Cmdr. Geordi La Forge |
| Michael Dorn | Lt. Worf |
| Gates McFadden | Dr. Beverly Crusher |
| Marina Sirtis | Counselor Deanna Troi |
| Brent Spiner | Lt. Cmdr. Data |
| Clyde Kusatsu | Adm. Nakamura |
| Patti Yasutake | Nurse Alyssa Ogawa |
| Denise Crosby | Lt. Tasha Yar |
| Colm Meaney | Chief Miles O'Brien |
| Pamela Kosh | Jessel |
| Tim Kelleher | Lt. Gaines |
| Alison Brooks | Ensign Chilton |
| Stephen M. Garvin | Ensign
(as Stephen Matthew Garvin) |
| Majel Barrett | Enterprise Computer
(voice) |
| John de Lancie | Q |
| Andreas Katsulas | Cmdr. Tomalak |
| Joyce Agu | Ensign Gates
(uncredited) |
| David Keith Anderson | Ensign Armstrong
(uncredited) |
| Teda Bracci | Post-Atomic Trial Spectator
(uncredited) |
| Cameron | Ensign Kellogg
(uncredited) |
| Tracee Cocco | Ensign Jae
(uncredited) |
| Marijane Cole | Operations Division Officer
(uncredited) |
| Brian Demonbreun | Andrew Powell
(uncredited) |
| Holiday Freeman | Command Division Officer
(uncredited) |
| Keith Gearhart | Operations Division Officer
(uncredited) |
| Bill Hagy | Starfleet Officer
(uncredited) |
| Fumiko Hamada | Command Division Officer
(uncredited) |
| Lauren Kim | Operations Division Officer
(uncredited) |
| Geri Lee | Post-Atomic Horror Trial Spectator
(uncredited) |
| David B. Levinson | Post-Atomic Horror Trial Spectator
(uncredited) |
| Pauline Olsen | Security Officer
(uncredited) |
| Jerry L. Quinn | Waiter
(uncredited) |
| Rick Ryan | Ensign Fletcher
(uncredited) |
| Richard Sarstedt | Command Division Officer
(uncredited) |
| Leslie Stump | Post-Atomic Horror Trial Spectator
(uncredited) |
| Guy Vardaman | Darien Wallace
(uncredited) |