| Patrick Stewart | Capt. Jean-Luc Picard |
| Jonathan Frakes | Cmdr. William Riker |
| LeVar Burton | Lt. Cmdr. Geordi La Forge |
| Michael Dorn | Lt. Worf |
| Gates McFadden | Dr. Beverly Crusher |
| Marina Sirtis | Counselor Deanna Troi |
| Brent Spiner | Lt. Cmdr. Data /
Dr. Noonien Soong |
| Fionnula Flanagan | Dr. Juliana Tainer |
| Bill Lithgow | Dr. Pran Tainer
(as William Lithgow) |
| Joyce Agu | Ensign Gates
(uncredited) |
| David Keith Anderson | Ensign Armstrong
(uncredited) |
| Tracee Cocco | Ensign Jae
(uncredited) |
| Elliot Durant III | Starfleet Ensign
(uncredited) |
| Holiday Freeman | Command Division Officer
(uncredited) |
| Grace Harrell | Operations Division Officer
(uncredited) |
| Kerry Hoyt | Operations Division Ensign
(uncredited) |
| Gary Hunter | Sciences Officer
(uncredited) |
| Jonathan Paley | Atrean aide
(uncredited) |
| Keith Rayve | Command Division Ensign
(uncredited) |
| Oliver Theess | Command Division Officer
(uncredited) |