| Patrick Stewart | Capt. Jean-Luc Picard |
| Jonathan Frakes | Cmdr. William Riker |
| LeVar Burton | Lt. Cmdr. Geordi La Forge |
| Michael Dorn | Lt. Worf |
| Gates McFadden | Dr. Beverly Crusher |
| Marina Sirtis | Counselor Deanna Troi |
| Brent Spiner | Lt. Cmdr. Data |
| Wil Wheaton | Ensign Wesley Crusher
(credit only) |
| Andreas Katsulas | Cmdr. Tomalak |
| Chris Demetral | Jean-Luc Riker /
Ethan |
| Carolyn McCormick | Minuet |
| Patti Yasutake | Nurse Alyssa Ogawa |
| Todd Merrill | Gleason |
| April Grace | Transporter Technician Hubbell |
| George O'Hanlon Jr. | Transporter Chief |
| Joyce Agu | Ensign Gates
(uncredited) |
| Rachen Assapiomonwait | Crewman Nelson
(uncredited) |
| Majel Barrett | Enterprise Computer
(voice) (uncredited) |
| Gilbert B. Combs | Romulan Officer
(uncredited) |
| Tim McCormack | Ensign Bennett
(uncredited) |
| Keith Rayve | Command Division Officer
(uncredited) |
| Richard Sarstedt | Command Division Officer
(uncredited) |
| Dana Tjulander | Barash
(uncredited) |
| Natalie Wood | Bailey
(uncredited) |