| Taylor Schilling | Piper Chapman |
| Uzo Aduba | Suzanne 'Crazy Eyes' Warren |
| Danielle Brooks | Tasha 'Taystee' Jefferson |
| Michael Harney | Sam Healy |
| Selenis Leyva | Gloria Mendoza |
| Taryn Manning | Tiffany 'Pennsatucky' Doggett |
| Adrienne C. Moore | Cindy Hayes |
| Dascha Polanco | Dayanara Diaz |
| Nick Sandow | Joe Caputo |
| Yael Stone | Lorna Morello |
| Samira Wiley | Poussey Washington |
| Kate Mulgrew | Galina 'Red' Reznikov |
| Laura Prepon | Alex Vause |
| Joanna Adler | Chaplain Royce |
| Mike Birbiglia | Danny Pearson |
| Blair Brown | Judy King |
| Michael Chernus | Cal Chapman |
| Jackie Cruz | Marisol 'Flaca' Gonzales |
| Catherine Curtin | Wanda Bell |
| Lea DeLaria | Big Boo |
| Jamie Denbo | Shelly Ginsberg |
| Beth Fowler | Sister Jane Ingalls |
| Joel Marsh Garland | Scott O'Neill |
| Kimiko Glenn | Brook Soso |
| Annie Golden | Norma Romano |
| Diane Guerrero | Maritza Ramos |
| Vicky Jeudy | Janae Watson |
| John Magaro | Vince Muccio |
| Richard Masur | Bill Montgomery |
| James McMenamin | Charlie 'Donuts' Coates |
| Olga Merediz | Lourdes |
| Emma Myles | Leanne Taylor |
| Matt Peters | Joel Luschek |
| Jessica Pimentel | Maria Ruiz |
| Alysia Reiner | Natalie Figueroa |
| Elizabeth Rodriguez | Aleida Diaz |
| Ruby Rose | Stella Carlin |
| Abigail Savage | Gina Murphy |
| Constance Shulman | Yoga Jones |
| Eric Zuckerman | Rabbi Alan Tatelbaum |
| Lori Petty | Lolly Whitehill |
| Lori Tan Chinn | Mei Chang |
| Lolita Foster | Eliqua Maxwell |
| Laura Gómez | Blanca Flores |
| Julie Lake | Angie Rice |
| Tamara Torres | Weeping Woman |
| Lin Tucci | Anita DeMarco |
| Brendan Burke | Wade Donaldson |
| Hamilton Clancy | CO Kowalski |
| Germar Terrell Gardner | Charles Ford |
| Alan Aisenberg | Baxter 'Gerber' Bayley |
| Emily Althaus | Maureen Kukudio |
| Berto Colon | Cesar |
| Sanja Danilovic | Katya |
| Lidiane Fernandes | Lea Guerrera |
| Michael Bryan French | Jack Pearson |
| Jimmy Gary Jr. | CO Felix Rikerson |
| Danielle Herbert | Jeanie 'Babs' Babson |
| Eden Malyn | CO Sikowitz |
| Joniece Abbott-Pratt | Ultrasound Technician |
| Michael Backes | Federal Agent |
| Adriana Camposano | Lucy Diaz |
| Natalie Carter | Lillian Hayes |
| Nyeema Carter | 1997 10 Year Old Black Cindy |
| Juri Henley-Cohn | Aydin |
| James Collins Jr. | Fence Guy #1 |
| Sydney Gayle | 1990 7 YO Lorna |
| Zachary Doran | Little Healy |
| Rob Falcone | Big Joe Morello |
| Alison Fernandez | Eva |
| Brianna Gonzalez-Bonacci | Christina Diaz |
| Nicholas Daniel Gonzalez | Emiliano Diaz |
| Kelvin Hale | Black Cindy's Dad |
| Ella Hampton | 8 Yr Old Brook |
| Melanie Hinkle | 18 Yr Old Boo |
| Catherine LeFrere | Stansie Morello |
| David Neal Levin | Paramedic |
| Sarah Mak | Brook's Mom |
| Karina Ortiz | Margarita |
| Richard Ramsay | Black Cindy's 16 Yr Old Brother |
| Leajato Amara Robinson | Bartholomew |
| Yelena Shmulenson | Rhea Boyle |
| Denay Smith | Black Cindy's 14 Yr Old Sister |
| Jeremiah Thomas | Black Cindy's 12 Yr Old Brother |
| Peter Wallack | Hobo Jesus |
| Tracy Westmoreland | Fence Guy #2 |
| Tim Wilson | Father John |
| Zakiya Young | Layla |
| Amelie McKendry | Inmate |
| Jessica Shea Alverson | Inmate |
| Eric J Carlson | Corrections Officer |
| Emma Cooper | Inmate |
| Jes Davis | Inmate |
| K. Andrew Deffley | Corrections Officer |
| Amanda Marasch | Inmate |
| Lynn Marocola | Inmate |
| Ashley North | Inmate |
| Sandra Segura | Inmate |
| Nancy Ellen Shore | Inmate |
| Natia Simon | Inmate |
| Sue Sterling | Inmate |