| Pedro Pascal | Javier Peña |
| Damián Alcázar | Gilberto Rodríguez Orejuela |
| Alberto Ammann | Pacho Herrera |
| Francisco Denis | Miguel Rodríguez Orejuela |
| Pêpê Rapazote | Chepe Santacruz Londoño |
| Matias Varela | Jorge Salcedo |
| Javier Cámara | Guillermo Pallomari |
| Andrea Londo | Maria Salazar |
| Michael Stahl-David | Chris Feistl |
| Matt Whelan | Daniel Van Ness |
| Eric Lange | Bill Stechner |
| Arturo Castro | David Rodriguez |
| José María Yazpik | Amado Carrillo Fuentes
(as José María Yázpik) |
| Kerry Bishé | Christina Jurado |
| Brett Cullen | Arthur Crosby |
| Glenn Morshower | Senator Martin |
| Miguel Ángel Silvestre | Franklin Jurado |
| Wayne Knight | Alan Starkman |
| Curtiss Cook | Gilbert Mills
(as Curtiss I' Cook) |
| Andrés Crespo | Carlo Córdova |
| Arnold Cantillo | Flaco |
| Carrell Lasso | Enrique |
| Roberto Cano | Darío |
| Edgar Prada | Álvaro Herrera |
| Juan Carlos Messier | Gustavo Calderón
(as Juan Messier) |
| Taliana Vargas | Paola Salcedo |
| Raymond Ablack | Stoddard |
| Margarita Rosa de Francisco | Carolina Álvarez |
| Louis Herthum | Senator Toyle |
| Gustavo Ángel | Santiago Medina |
| Juan Pablo Shuk | Colonel Martinez |
| Lina Castrillón | Patricía Pallomari |
| Vicky Hernández | Gerda |
| Cristian Sarmiento | Fercho |
| Lux Pascal | Elias
(as Lucas Balmaceda Pascal) |
| Bella Barragán | Alma Salcedo |
| Juana Álvarez | Vera Salcedo |
| Douglas Ceballos | Bank President |
| Raul Tovar Salazar | Hernán |
| Jeff Glaser | American Pilot |
| Marco López | Investor #1
(as Marco Lopez) |
| Hernán Alvarez | Investor #2
(as Hernan Alvarez) |
| Julio Osorio | Ticket Agent |
| David Páez | Concierge
(as David Paez) |
| Juliana Cuevas | Receptionist |
| Valentina Perez | Beautiful Girl |
| Jose Lizarde Jr. | Cartel Leader
(uncredited) |