| Jon Bernthal | Frank Castle /
Punisher |
| Ben Barnes | Billy Russo |
| Amber Rose Revah | Dinah Madani |
| Josh Stewart | John Pilgrim |
| Floriana Lima | Krista Dumont |
| Giorgia Whigham | Amy Bendix |
| Royce Johnson | Det. Sgt. Brett Mahoney |
| Corbin Bernsen | Anderson Schultz |
| Annette O'Toole | Eliza Schultz |
| Teri Reeves | Marlena Olin |
| Allie McCulloch | Rebecca Pilgrim |
| Joe Holt | Sheriff Hardin |
| Brandon Gill | Deputy Ken Ogden |
| Jamie Ann Romero | Deputy Murphy
(as Jamie Romero) |
| Rudy Eisenzopf | Deputy Dobbs |
| Michael Pemberton | Lieutenant Ferrara |
| Donald Webber Jr. | Bruce Ogden |
| Wilbur Edwin Henry | Reverend Potter
(as Wilber Edwin Henry) |
| Zell Steele Morrow | Michael Pilgrim |
| Henry Boshart | Lemuel Pilgrim |
| Alex Pires | I.T. Guy |
| Charlie Romanelli | Militia |
| Ramona Floyd | Dr. Evans |
| Harry Adam | Church Boy
(uncredited) |
| Michael DeBarge | Parishioner
(uncredited) |
| Sara Mann | Church Choir
(uncredited) |
| Ray Rosario | Parishioner
(uncredited) |
| Adam B. Shapiro | Church Choir
(uncredited) |