| Dennis Farina | Detective Joe Fontana |
| Jesse L. Martin | Detective Ed Green |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Annie Parisse | A.D.A. Alexandra Borgia |
| Fred Thompson | D.A. Arthur Branch |
| Reed Diamond | Mr. Klein |
| Enid Graham | Mrs. Drucker |
| Jordan Charney | Trial Judge Donald Karan |
| Leslie Hendrix | M.E. Dr. Elizabeth Rodgers |
| William Sadler | Kevin Drucker |
| Brad Fleischer | Patterson Drucker |
| Jené | Lola |
| J. Salome Martinez | Oscar 'Diablo' Morales |
| John Cariani | CSU Technician Julian Beck |
| Karen Shallo | Judge Anna Shiro |
| Tom Lacy | Arraignment Judge Mark Calhoun |
| Sanjiv Jhaveri | Sinja |
| Maury Ginsberg | Ari Posner |
| Marcos Palma | Beto |
| Sol Miranda | Rita Hernandez |
| Socorro Santiago | Estela Richter |
| Scott Freeman | Doug Richter |
| George Demas | Heath Goodman |
| Preston Keith Smith | Warren Finley |
| Burton Perez | Gang Member #1 |
| Erik Casanova | Gang Member #2 |
| Fidel Vicioso | Gang Member #3 |
| Jose Sanchez | Day Laborer |
| Carolyn Quinones | Hooker |
| Phyllis Sanfiorenzo | Alley Hooker |
| David Raymond Wagner | Lt. Duffy |
| John Pieza | Assistant M.E. Paul Sharlett |
| James Michael Farrell | Sgt. Nash |
| Gregory Weinberg | Clerk |
| Cristina Duarte | Dog Walker |
| Edgar Felix | Blue Collar |
| Steven Zirnkilton | Narrator |