| Dennis Farina | Detective Joe Fontana |
| Jesse L. Martin | Detective Ed Green |
| S. Epatha Merkerson | Lieutenant Anita Van Buren |
| Sam Waterston | E.A.D.A. Jack McCoy |
| Elisabeth Röhm | A.D.A. Serena Southerlyn |
| Fred Thompson | D.A. Arthur Branch |
| Bruce Altman | Dr. Alvin Lawrence |
| Roxanna Hope Radja | Angela Gusmarino |
| Max Baker | Clive Raymond |
| Leslie Hendrix | M.E. Dr. Elizabeth Rodgers |
| Graeme Malcolm | Hotel Manager |
| Mark Nelson | Dr. Stuart Barton |
| Carolyn McCormick | Dr. Elizabeth Olivet |
| Kate Burton | Erica Gardner |
| Irene Glezos | Darlene Hackett |
| Don Amendolia | Gregory Finney |
| Lisa Bansavage | Ann Belmar |
| Peter Galman | Dr. Arthur Glassman |
| Selenis Leyva | Detective Mariluz Rivera |
| Michael Hirsch | David Harrison |
| Gustave Johnson | Trial Judge Robert Daniels |
| Adam Stein | Assistant Medical Examiner |
| Wayne Pretlow | Rich Cannon |
| Don Stitt | Victor |
| Garrett Neergaard | Jeff Golden |
| Larry Preston | David Tolchuck |
| Leila Gazale | Niloo Razi |
| Jana Zeineddine | Receptionist |
| Olivia Negron | Anna |
| Molly Russell | Heather Harrison |
| Frank Hopf | Uniformed Officer #1 |
| Brigid Brady | Nurse #1 |
| Phyllis Johnson | Nurse #2 |
| Janis Corsair | Nosy Shouting Neighbor |
| Melissa Kid | Extra |
| Henry Kwan | Foreperson |
| Steven Zirnkilton | Narrator |