| Robin Wright | Claire Underwood |
| Michael Kelly | Doug Stamper |
| Diane Lane | Annette Shepherd |
| Campbell Scott | Mark Usher |
| Derek Cecil | Seth Grayson |
| Greg Kinnear | Bill Shepherd |
| Cody Fern | Duncan Shepherd |
| Athena Karkanis | Melody Cruz |
| Jeremy Holm | Nathan Green |
| Linda Powell | Marcy Siegerson |
| Chip Zien | Dr. Charles Rosen |
| Chris Agos | Special Agent Rick Bowman |
| Robert Newman | EPA Administrator |
| Beth Chamberlin | Tabitha Peters |
| Ann Charles Sutton | Young Claire |
| Gabby Beans | Private Jenna Burton |
| Nini Le Huynh | Lynn Phang |
| Robert Neal Marshall | Scotty Tibbs |
| Pat Dortch | Secretary of Energy |
| Tim Pabon | Reporter |
| Lora Lee Gayer | Reporter |
| Michael James Thomas | Male Soldier |
| David Price | Fred Amburg |
| Samuel Smith | Secret Service Agent |
| Jimmy McCool | Young Boy #1 |
| Billy McFadden | Young Boy #2 |
| Patrick Ryan Wood | Young Boy #3 |
| Ryan Sell | Young Boy #4 |
| Beth Barnes | Honored Conference Guest |
| Frank Bliss | General |
| Marisol Correa | Lieutenant General Nancy Gallagher |
| Dan Matteucci | Marine
(credit only) |
| B. Cherie Patterson | Military Recruit |
| Nathaniel 'Billy' Sherrod Jr. | Boom Mic Press
(credit only) |
| Kevin D. Benton | Military Recruit /
National Guard
(uncredited) |
| Lamont Easter | Underwood Secret Service
(uncredited) |
| Cole Elliott | Trust Funder
(uncredited) |
| Dave Ferrier | Videographer
(uncredited) |
| Ally Ibach | Military Recruit
(uncredited) |
| Gina Jun | Staff
(uncredited) |
| Sharrie McCain | Military recruit
(uncredited) |
| Quentin | Military Shelter Patron
(uncredited) |
| Roger Tyler | Server
(uncredited) |
| Rick Voight | US Senator
(uncredited) |