| Michael C. Hall | Dexter Morgan |
| Julie Benz | Rita Bennett |
| Jennifer Carpenter | Debra Morgan |
| Erik King | Sgt. James Doakes |
| Luna Lauren Velez | Lt. Maria LaGuerta
(as Lauren Velez) |
| David Zayas | Det. Angel Batista |
| James Remar | Harry Morgan
(credit only) |
| Geoff Pierson | Capt. Tom Matthews |
| C.S. Lee | Vince Masuka |
| Mark Pellegrino | Paul Bennett |
| Sam Witwer | Neil Perry |
| Christian Camargo | Rudy Cooper |
| Mark L. Young | Jeremy Downs |
| Lizette Carrion | Shanda |
| Brad William Henke | Tony Tucci |
| Christina Robinson | Astor Bennett |
| Daniel Goldman | Cody Bennett |
| David Batiste | Computer Analyst |
| Sewell Whitney | Public Defender |
| Alex Demir | Guard |
| Colton James | Metalhead |
| Bunnie Rivera | Laline |
| Jayden Lund | Supervisor |
| Darcy Fowers | Captive Prostitute |
| Eric Banzon | Yearbook Editor
(uncredited) |
| J.R. Esposito | Detective
(uncredited) |
| Ken-Ali | Bellhop
(uncredited) |
| Chris Muto | Police Officer
(uncredited) |
| Mary Scanlon | Dancer
(uncredited) |