| Bryan Cranston | Walter White |
| Anna Gunn | Skyler White |
| Aaron Paul | Jesse Pinkman |
| Dean Norris | Hank Schrader |
| Betsy Brandt | Marie Schrader |
| RJ Mitte | Walter White, Jr. |
| Jonathan Banks | Mike Ehrmantraut |
| Giancarlo Esposito | Gus Fring |
| Krysten Ritter | Jane Margolis |
| John de Lancie | Donald Margolis |
| Steven Michael Quezada | Steven Gomez |
| Sam McMurray | Dr. Victor Bravenec |
| Michael Shamus Wiles | ASAC George Merkert |
| David House | Dr. Delcavoli |
| Phil Howell | O.M.I. Attendant
(as Philip Howell) |
| Juliet Lopez | O.M.I. Officer |
| Kieran Sequoia | Local Correspondant |
| Richard Williams | Business Community Leader #1 |
| Daniel D. Halleck | Business Community Leader #2
(as Daniel Halleck) |
| Richard Christie | Stew
(as Dick Christie) |
| Ravenna Fahey | Nurse |
| Jon Reigle | Look out |
| Tina Borek | Lady in Car
(uncredited) |
| Andrea Good | Laundry Worker
(uncredited) |