| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson
(credit only) |
| Dayton Callie | Wayne Unser |
| Kim Coates | Alexander 'Tig' Trager |
| Drea de Matteo | Wendy Case |
| Tommy Flanagan | Filip 'Chibs' Telford |
| David Labrava | Happy Lowman |
| Niko Nicotera | George 'Ratboy' Skogstrom |
| Theo Rossi | Juan Carlos 'Juice' Ortiz
(credit only) |
| Jimmy Smits | Nero Padilla |
| CCH Pounder | Tyne Patterson |
| Annabeth Gish | Lieutenant Althea Jarry |
| Peter Weller | Charles 'Charlie' Barosky |
| Michael Ornstein | Chuck 'Chucky' Marstein |
| Winter Ave Zoli | Lyla Winston |
| Emilio Rivera | Marcus Alvarez |
| Michael Beach | Taddarius Orwell 'T.O.' Cross |
| Billy Brown | August Marks |
| Rusty Coones | Rane Quinn |
| Mo McRae | Tyler Yost |
| Jacob Vargas | Allesandro Montez |
| Olivia Burnette | Homeless Woman |
| Ivo Nandi | Oscar El Oso Ramos |
| Bob McCracken | Brendan Roarke |
| Walton Goggins | Venus Van Dam |
| Michael Chiklis | Milo |
| Scott Anderson | Connor Malone |
| Jason Barry | Declan |
| Evan Londo | Abel |
| Ryder Londo | Abel |
| Josh Nasar | Sheriff Carreira |
| Alan O'Neill | Hugh |
| Derek Graf | CHP Officer |
| Jasper Pendergrass Jr. | Bodyguard
(as Jasper J. Pendergrass Jr.) |
| Dan Cooley | Crime Scene Photographer |
| Sophia Markov | Thomas Teller
(uncredited) |
| Victoria Markov | Thomas Teller
(uncredited) |