| Charlie Hunnam | Jackson 'Jax' Teller |
| Katey Sagal | Gemma Teller Morrow |
| Mark Boone Junior | Robert 'Bobby Elvis' Munson |
| Dayton Callie | Wayne Unser |
| Kim Coates | Alexander 'Tig' Trager |
| Tommy Flanagan | Filip 'Chibs' Telford |
| Theo Rossi | Juan Carlos 'Juice' Ortiz |
| Maggie Siff | Dr. Tara Knowles Teller |
| Ron Perlman | Clarence 'Clay' Morrow
(credit only) |
| Jimmy Smits | Nero Padilla |
| CCH Pounder | Tyne Patterson |
| Peter Weller | Charles 'Charlie' Barosky |
| Drea de Matteo | Wendy Case |
| Rockmond Dunbar | Lieutenant Eli Roosevelt |
| Michael Ornstein | Chuck 'Chucky' Marstein |
| David Labrava | Happy Lowman |
| Robin Weigert | Ally Lowen |
| Billy Brown | August Marks |
| Jeff Kober | Jacob Hale, Jr. |
| Adrienne Barbeau | Alice Noone |
| Niko Nicotera | George 'Ratboy' Skogstrom |
| McNally Sagal | Margaret Murphy |
| Rusty Coones | Rane Quinn |
| Israel Broussard | Joey Noone |
| Jenny Gago | Gloria Rodriguez |
| Jacob Vargas | Allesandro Montez |
| Douglas Bennett | Orlin West |
| Walton Goggins | Venus Van Dam |
| LaMonica Garrett | Deputy Sheriff Cane |
| Evan Londo | Abel |
| Ryder Londo | Abel |
| Scott Anderson | Connor Malone |
| Marya Delver | Deputy Sheriff Eglee |
| Kevin Fry | Neil
(as Kevin Fry-Bowers) |
| Alan O'Neill | Hugh |
| Price Carson | SANWA County Guard |
| Charles Ambrose | Andy
(as Jason Ambrose) |
| Tanner Gill | Rod |