| Glen Davies | Burt Talbot |
| Sarah Winter | Staff Nurse Jo-Beth Mills |
| Robert Wilfort | Lester Fagen |
| Morgan Jones | Lyle Capper |
| Celine Buckens | Student Nurse Daisy Bennett |
| Ciara Charteris | Nurse Flora Byron |
| Shaun Evans | DC Endeavour Morse |
| Roger Allam | DI Fred Thursday |
| Phoebe Nicholls | Caroline Bryce-Morgan |
| David Yelland | Sir Merlyn Chubb |
| Edward MacLiam | Dr. Malcolm Kane |
| Amy Marston | Sister Clodagh MacMahon |
| John Hopkins | Dr. Dean Powell |
| James Bradshaw | Dr. Max DeBryn |
| Alex McSweeney | Terence Bakewell |
| Anton Lesser | Chief Superintendent Reginald Bright |
| Dakota Blue Richards | WPC Shirley Trewlove |
| Sean Rigby | DS Jim Strange |
| Claire Lichie | Donna Zacharides |
| Caroline O'Neill | Win Thursday |
| Shvorne Marks | Monica Hicks |
| Mark Phoenix | Gilbert Sisley |
| Sion Alun Davies | Murray Booth |
| Sara Vickers | Joan Thursday |
| Matthew Walker | Ray Morton |
| Ty Hurley | Undertaker |
| Adam Lazarus | Visitor |
| Tim Packham | Gravedigger |