| Kathryn Morris | Lilly Rush |
| Danny Pino | Scotty Valens |
| John Finn | John Stillman |
| Jeremy Ratchford | Nick Vera |
| Thom Barry | Will Jeffries |
| Tracie Thoms | Kat Miller |
| Nestor Carbonell | Mike Valens |
| Julie Adams | Dottie Mills (2006) |
| Rutanya Alda | Jenny (2006) |
| Sarah Drew | Jenny (1958) |
| Charles Esten | John 'The Hawk' Hawkins |
| Eric Jungmann | Timmy 'Bones' Hamlin (1958) |
| Camillia Monet | Alegria |
| Cari Shayne | Dottie Mills (1958) |
| Robert Symonds | Ted Chester (2006) |
| Robert F. Lyons | Scott 'Skiz' Stenkovic (2006) |
| Chad Brannon | Scott 'Skiz' Stenkovic (1958) |
| Lorenzo James Henrie | Young Mike Valens |
| Richard Roat | Tim Hamlin (2006) |
| Allen Alvarado | Young Scotty Valens |
| Adam Chambers | Tom Bergin (1958) |
| Ken Elliott | Little Richard (1958) |
| Kandis Fay | Teen Girl (1958) |
| Christopher May | Ted Chester (1958) |
| Paul Perri | Benson Ockley (1958) |
| Alison Anderson | Mrs. Chester |
| Aynsley Bubbico | Teen Girl #2 |
| Kimberly Parmon | Swing Dancer |
| Kelley Petrisi | LuLu |
| Marshall Watson | Swing Dancer |
| Mona Weiss | Dancer |